Tipping the Scales: Stem Cells May Help Prevent Obesity and More.

Scientists have found that the alteration of stem cell cilia can have a positive effect on weight loss.

 

In a recently published study from the Queen Mary University of London, scientists discovered a connection between the length of cilia [hair-like projections for cell movement] on stem cells and their proclivity towards differentiating into fat cells.  By restricting the elongation of stem cell cilia, the researchers were able to impede on the formation of new fat cells. Continue reading

Multiple Sclerosis Treatment Becomes Canada’s First MS Stem Cell Clinical Trial.

The University of Ottawa trial infuses MSCs to reduce inflammation in the central nervous systems of MS patients.

The Multiple Sclerosis Society of Canada has funded Canada’s first stem cell clinical trial to treat multiple sclerosis, conducted by researchers at the University of Ottawa. The trial, called MESCAMS [Mesenchymal Stem Cell Therapy for Canadian MS patients], will comprise MSC infusions to the central nervous system to utilize their ability to regulate autoimmune attacks and reduce inflammation in 40 MS patients. Continue reading

An Eye for a Tooth: Corneal Blindness Treatment Advances With The Use Of Dental Stem Cells.

Dental Stem Cells may hold the potential to cure corneal blindness.

Ophthalmologists James L Funderburgh, Ph.D. and Fatima Syed-Picard, Ph.D. from the University of Pittsburgh have devised a method for treating corneal blindness by utilizing dental pulp stem cells.  The researchers harvested the stem cells from molars discarded during routine extraction and induced the cells to differentiate into keratocytes [corneal cells].  They then seeded the cells onto a nanofiber scaffold, allowing them to grow into fully developed, functional corneas capable of restoring eyesight.    Continue reading

Burn Treatment Replaces Skin Grafts with Stem Cells.

Stem cells may eliminate the need for painful skin grafts for burn victims.

In a new two year clinical trial conducted by the University of Miami, researchers will attempt to treat deep second degree burn victims with mesenchymal stem cells [MSCs] as a potential alternative to skin grafts.  The team, led by Dr. Evangelos Badiavas, will first cover the wounds in protective dressing, and then inject the MSCs under the dressing and into the wounds to spur the regeneration of the inner and outer layers of skin.

Severe burns currently account for 450,000 emergency room treatments annually, as well as 15-20% of combat injuries to military veterans.  But despite a high demand to eliminate painful and taxing skin graft surgeries, they are currently the only option for reconstruction.  While Dr. Badiavas’ stem cell therapy is in its initial assessment phase, early indications point to  possible MSC treatments that may  provide a more comfortable and efficient method to regenerate healthy skin tissue, resulting in better outcomes for patients.

As regenerative engineering progresses, we believe the best stem cells to use in emerging treatments will be the patient’s own [autologous stem cells] as this negates the need to find a suitable donor and eliminates the chances of rejection of the transplanted tissue. To learn more about banking your own valuable stem cells to insure your family’s future health, visit StemSave or call 877-783-6728 (877-StemSave) today.

 

 

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The Future of Regenerative Medicine is Now™

Hypoplastic Left Heart Syndrome Treatment Integrates Cardiac Stem Cells.

Initial trials of stem cell treatment for hypoplastic left heart syndrome have proven to be both safe and effective for children with the congenital defect.

Researchers from Okayama University have developed a method to treat the congenital heart defect known as hypoplastic left heart syndrome [HLHS] by utilizing a specialized cardiac stem cell.  In a Phase I clinical trial conducted on children suffering from HLHS, the scientists concluded that, because the young stem cells in children are more abundant and self-renewing than those in adults, intracoronary injection of stem cells is a safe and feasible approach to treating the condition. Continue reading

Stroke-Induced Brain Damage Prevented by Stem Cells.

Stem cells have been found to prevent neurological damage to GCI stroke victims.

In a recently published study from the Hallym University College of Medicine, researchers have applied mesenchymal stem cells [MSCs] to animal models afflicted with global cerebral ischemia [GCI] to successfully reduce the associated neuronal damage.  When compared to those that received no treatment, animals that received MSCs displayed a significant decrease in cell death, inflammation to the brain, and disruption of the blood brain barrier. Continue reading

Type 1 Diabetes Reversed by Integrating Mesenchymal Stem Cells.

MSCs and HCELL molecules track down islet cells and reverse inflammation.

According to a recently published study from the Brigham and Woman’s Hospital, mesenchymal stem cells [MSCs] have the ability to reverse type I diabetes by suppressing the auto-immune attack of islet cells.  Although the MSCs cannot be directly injected into the pancreas, the researchers utilized the surface adhesion molecule HCELL to hone the stem cells in on the inflamed islets, allowing them to normalize blood sugar levels without the use of insulin. Continue reading

Atherosclerotic Lesions Prevented by MSCs

Stem cells were found to reduce plaque in patients with atherosclerosis.

According to new research from the National Yang-Ming University, mesenchymal stem cells [MSCs] hold the ability to limit atherosclerotic plaque formation, thereby preventing the onset of harmful endothelial lesions. The research team, led by Shih-Chieh Hung, transplanted MSCs into animal models with atherosclerosis and observed significant reduction in plaque formation. They also saw an increase in blood vessel dilation, which prevents further plaque development, indicating good endothelial health. Continue reading

Sniffing Out Parkinson’s Disease With Stem Cells

Stem Cells found in the nose produce neurons that may be able to treat neurodegenerative diseases.

German scientists at the University of Bielefeld and Dresden University of technology have produced neurons from inferior turbinate stem cells [ITSC], a cell type that is typically discarded during sinus surgery, as a potential treatment for Parkinson’s disease.  After transplanting the ITSCs into an animal model suffering from Parkinson’s, the researchers observed full functional restoration and significant behavioral recovery in the subjects without any adverse side effects. Continue reading

Lung Regeneration Made Possible through Stem Cells.

Scientists have found a stem cell line that specializes in restoring lung tissue

Jackson Laboratory scientists have identified the adult lung stem cells p63+/Krt5+ as the specific cell line that specializes in lung regeneration.  In an animal model, professors Frank McKeon, Ph.D. and Wa Xian, Ph.D. observed as the p63+/Krt5+, which typically mature into the lungs’ alveoli, responded to lung damage caused by the H1N1 influenza virus by migrating to the sites of inflammation and restoring the lost tissue. Continue reading