The Multiple Sclerosis Society of Canada has funded Canada’s first stem cell clinical trial to treat multiple sclerosis, conducted by researchers at the University of Ottawa. The trial, called MESCAMS [Mesenchymal Stem Cell Therapy for Canadian MS patients], will comprise MSC infusions to the central nervous system to utilize their ability to regulate autoimmune attacks and reduce inflammation in 40 MS patients. Continue reading
Researchers from Okayama University have developed a method to treat the congenital heart defect known as hypoplastic left heart syndrome [HLHS] by utilizing a specialized cardiac stem cell. In a Phase I clinical trial conducted on children suffering from HLHS, the scientists concluded that, because the young stem cells in children are more abundant and self-renewing than those in adults, intracoronary injection of stem cells is a safe and feasible approach to treating the condition. Continue reading
In a recent update of an ongoing five year clinical trial conducted by the Chicago Blood Cancer Institute, patients with relapsing-remitting multiple sclerosis have experienced suppression of disease-related inflammation as a result of hematopoietic stem cell transplantations. The stem cells have the ability to regulate the autoimmune attack on the central nervous system, and have provided 82.8% of the patients with two years thus far of event-free disease remission. Continue reading
According to new research from the Stowers Institute for Medical Research, hematopoietic stem cells [stem cells that produce blood] are directly regulated by megakaryocytes, the blood cells responsible for healing wounds. The researchers found that megakaryotes produce two growth factors; one that signals for hematopoietic stem cells to proliferate, and one that keeps them in an inactive state. This relationship controls the amount of blood being produced in the body. Continue reading
A team of researchers led by Professor Andrew Lotery at Southampton General Hospital have discovered a source of retinal stem cells on the surface of the eye. If scientists can harvest these readily accessible stem cells, convert them to light-sensitive cells, and then transplant them back into the eye, the cells could provide new treatments for age-related macular degeneration [AMD].
Currently, AMD is the leading cause for blindness in patients over the age of 50, and there is no known cure. However, the discovery of stem cells on the retina could facilitate a new method for scientists to replenish the light-sensitive cells in a patient’s eyes without the risk of rejection by the immune system, presenting a new potential treatment for the disease.
Although AMD tends to affect patients later on in life, the higher regenerative abilities of younger stem cells are preferable over older ones for medical therapies. One way to assure access to the enhanced regenerative abilities of your own stem cells is to preserve them while they are still young, so that they can be used later in life in emerging regenerative therapies. Today, preserving your own stem cells, also known as autologous stem cells, is simple and affordable for families. To learn how you can preserve your own valuable stem cells through non-invasive and effective methods, please visit StemSave or call 877-783-6728 (877-StemSave) today.
To view the full article, click here.
The Future of Regenerative Medicine is Now™.
In a new pilot study at the Royal National Orthopaedic Hospital in London, researchers will utilize stem cells to promote the healing of painful tendon injuries such as tennis elbow. Initial studies suggest that, upon transplantation, the stem cells release growth factors to the point of injury, which induce the growth of new tendon tissue while reducing scar tissue to recover movement and flexibility. Continue reading
Harvard University researchers have developed a technique to accelerate stem cell differentiation to produce massive amounts of the insulin-producing beta cells that are destroyed in patients with type-1 or type-2 diabetes. With an ample and readily available supply of beta cells, researchers are developing therapies that may someday allow patients to produce the precise amount of insulin required to control their blood sugar levels naturally – without the use of a pump or insulin shots. Continue reading
Researchers from the University of California San Diego have differentiated stem cells into neurons to reach a new understanding of the mechanisms of schizophrenia. The scientists harvested the stem cells of schizophrenia patients, differentiated them into brain cells, and then studied the cells on a dish to reveal that not only do stem cell-derived neurons emit neurotransmitters, but that several of these transmitters, such as dopamine, epinephrine, and norepinephrine, are secreted excessively in patients suffering from schizophrenia. Continue reading
Today, stem cells are rightfully perceived as the future of regenerative medicine, set to bring the marvels of science fiction into reality. But in looking ahead at all of the promise that stem cells hold for the future, it becomes easy to miss the scientific advances made to date for the millions of people around the world suffering from disease, trauma, and injury. Thus, today marks Stem Cell Awareness Day: a global celebration of stem cell research coordinated to highlight the treatments and therapies currently in development to create personalized regenerative therapies for patients. Continue reading
A recent clinical trial conducted by the University of Genoa has determined that mesenchymal stem cell therapy to treat multiple sclerosis is indeed safe to perform on humans. 27 MS patients completed the study, which comprised an injection of the patient’s own [autologous] mesenchymal stem cells [MSCs] to reduce excessive inflammation caused by the patients’ own immune systems. None of the patients suffered any side effects from the injection. Continue reading