Epibone creates precisely measured scaffolding for stem cells to recreate damaged bone.
The New York-based startup Epibone intends to begin human testing on a procedure that will utilize stem cells to regenerate living bone tissue. The researchers, originally from Columbia University, will apply autologous [the patient’s own] stem cells to nanofiber scaffolding of the desired size and shape and direct the stem cells to differentiate into a physical and genetic replica of the patient’s own bone. Continue reading →
Remote controlled nanoparticles may allow stem cells to regenerate bone tissue
Medical researchers from Keele University and Nottingham University have integrated remote controlled magnetic nanoparticles to incite the differentiation of stem cells into new bone tissue for the treatment of bone diseases, disorders, and injuries. In pre-clinical trials, the nanoparticles were coated with proteins that stimulate the stem cells, and then delivered directly to the damaged tissue via an external magnetic field. Continue reading →
Certain stem cells have been found to be immune to the bone-degenerative side effects of chemotherapy used against leukemia.
A research team, led by Dr. Eric Darling of Brown University, has found a potential source of stem cells to protect children with acute lymphoblastic leukemia against the adverse effects of the chemotherapy drug methotrexate (MTX). Adipose-derived stem cells, which appear to be impervious to the bone-degenerative side effects of MTX, may allow children to undergo the chemotherapy treatment and then regain the lost bone tissue afterwards. Continue reading →
Stem cells are allowing doctors to personalize treatments to repair damaged or diseased bone.
A team of medical researchers at Saint Luc University Clinic have developed a method of repairing bones utilizing autologous [the patient’s own] stem cells. The process involves harvesting the stem cells from the patient, differentiating the stem cells in-vitro to grow bone, pairing the cells with a scaffolding matrix and then molding the material to repair damaged or diseased bone within the patient. Continue reading →
Surgeons utilizing the patient’s own stem cells could significantly reduce rehabilitation times for injured athletes.
Orthopedic Surgeons are utilizing autologous [the patient’s own] stem cells to treat injuries and degenerative diseases in the joints and bones of athletes. The treatments involve the recovery of the patient’s own mesenchymal stem cells – which are particularly plastic and can differentiate into a variety of tissue types and implanting them back into the damaged bone or joint to reduce inflammation and regenerate damaged tissue without the need for invasive surgery. Continue reading →
The Biopen “fills in” damaged bone with stem cells to facilitate bone regeneration.
Researchers at Melbourne’s St. Vincent Hospital and the University of Wollongong are engineering a device known as the “Biopen” to deliver stem cells to damaged or diseased bones. This novel method of stem cell therapy administers a mixture of jelly and stem cells into the damaged sections of the bone. The jelly is then UV-dried into a scaffolding to facilitate stem cell growth and bone regeneration.
Autologous stem cells eliminate the risk of bone loss and infection in hard to heal bone fractures
A study team from Kobe University Graduate School of Medicine in Japan has developed a treatment for hard to heal bone fractures. The treatment makes use of autologous [the patient’s own] stem cells to promote proper healing in fractures that fail to heal on their own. Continue reading →
Researchers at Georgia Reagents University, Medical College of Georgia have discovered a signaling molecule that helps stem cells to survive in a low-oxygen environment, such as inside the bone marrow. This discovery is a significant advance in understanding the way stem cells works in their natural environment thus aiding researchers in the development of more effective therapies to combat bone loss as the world population ages.
Researchers at the University of California have developed a new technique that utilizes stem-cell-binding molecules to aid in regenerating bone tissue. By directing the body’s own stem cells to the bone surface, mesenchymal stem cells then differentiate into bone-forming cells and synthesize proteins to enhance bone growth and regeneration. For patients with osteoporosis, this new regenerative therapy could mean increased bone density and prevention of further bone loss.