According to new research from the National Yang-Ming University, mesenchymal stem cells [MSCs] hold the ability to limit atherosclerotic plaque formation, thereby preventing the onset of harmful endothelial lesions. The research team, led by Shih-Chieh Hung, transplanted MSCs into animal models with atherosclerosis and observed significant reduction in plaque formation. They also saw an increase in blood vessel dilation, which prevents further plaque development, indicating good endothelial health. Continue reading
Scientists have utilized stem cells to engineer an esophagus without exogenous growth factors.
Researchers from the Saban Research Institute of Children’s Hospital Los Angeles have grown esophageal tissue in vivo (in the body) from stem cells without the use of exogenous growth factors. In an animal model, the scientists transplanted stem cells, as well as a simple biodegradable scaffold, and relied on the stem cells’ ability to migrate towards the tissue in need of repair. The cells then differentiated into the epithelial, muscle, and nerve cells to develop a healthy esophagus. Continue reading
Molecular Biologists from Genentech, Inc., in California have utilized stem cells to better understand the advent and growth of prostate cancer. The researchers discovered a marker specific to cancerous cells that, when used as a therapeutic target, could lead to the development of new prostate cancer treatments. Continue reading