Bone Regeneration Made Possible With Stem Cells

Epibone creates precisely measured scaffolding for stem cells to recreate damaged bone.

The New York-based startup Epibone intends to begin human testing on a procedure that will utilize stem cells to regenerate living bone tissue.  The researchers, originally from Columbia University, will apply autologous [the patient’s own] stem cells to nanofiber scaffolding of the desired size and shape and direct the stem cells to differentiate into a physical and genetic replica of the patient’s own bone. Continue reading

Multiple Sclerosis Therapy Incorporates Stem Cells in Clinical Trial

Mesenchymal Stem Cell Therapy has been deemed safe for patients suffering from multiple sclerosis.

A recent clinical trial conducted by the University of Genoa has determined that mesenchymal stem cell therapy to treat multiple sclerosis is indeed safe to perform on humans.  27 MS patients completed the study, which comprised an injection of the patient’s own [autologous] mesenchymal stem cells [MSCs] to reduce excessive inflammation caused by the patients’ own immune systems. None of the patients suffered any side effects from the injection. Continue reading

Multiple Sclerosis Therapy Incorporates Stem Cells in Clinical Trial

Mesenchymal Stem Cell Therapy has been deemed safe for patients suffering from multiple sclerosis.

A recent clinical trial conducted by the University of Genoa has determined that mesenchymal stem cell therapy to treat multiple sclerosis is indeed safe to perform on humans.  27 MS patients completed the study, which comprised an injection of the patient’s own [autologous] mesenchymal stem cells [MSCs] to reduce excessive inflammation caused by the patients’ own immune systems. None of the patients suffered any side effects from the injection. Continue reading

Osteoarthritis Stem Cell Treatment in Clinical Trial

The transplantation of stem cells into areas affected by osteoarthritis allow lost cartilage tissue to regenerate.

In recent clinical trials, researchers at the National University of Ireland Galway have successfully utilized adult stem cells to treat patients with osteoarthritis.  The treatment involves recovering the patients’ own [autologous] stem cells and then injecting the stem cells into cartilage to stimulate the regeneration of lost tissue. Continue reading

Type 1 Diabetes Treatment Advance Utilizes Mesenchymal Stem Cells

The transplantation of adult stem cells into a Type-1 Diabetes animal model has revealed the importance of blood vessels in pancreatic beta cell regeneration.

Researchers led by Dr. Habib Zaghouani from the University of Missouri have developed a potential cure to Type 1 Diabetes by utilizing mesenchymal stem cells [MSCs].  Although researchers anticipated that the MSCs would differentiate into new insulin producing pancreatic beta cells, they discovered that the stem cells fulfilled the more critical function of repairing damaged blood vessels, which in turn facilitated the regeneration of insulin producing pancreatic beta cells and the distribution of insulin across the body. Continue reading

Anti-Aging Properties of MSCs

Mesenchymal Stem Cells are able to stimulate muscle-building cells that lose function with age.

A recently published study by University of Illinois Kinesiology and Community Health Professor Marni Boppart has identified mesenchymal stem cells [MSCs] as a tool for rejuvenating muscle to prevent age-related injuries and disabilities.  In addition to their ability to differentiate into other cell types, MSCs were found to secrete growth factors that stimulate the activation of the multiple cell types comprising skeletal muscle, including muscle precursor cells and satellite cells, which lose function with age. Continue reading

Stem Cells Utilized to Regulate Extreme Inflammation in Limb Injuries.

Stem cells are being used to reduce extreme inflammation to alleviate strain on the body’s healing process.

Immunologists at the Medical College of Georgia and College of Dental Medicine a Georgia Regents University have developed a method of utilizing autologous [the patient’s own] stem cells to treat Ischemia Reperfusion Injury, a condition in which excessive blood flow to an injury results in severe inflammation and hindered recovery. The stem cells function with a chemical called indoleomine 2,3 Dioxygenase, or IDO, which can regulate the immune response without completely disabling it, allowing the healing process to ensue normally. Continue reading

Mesenchymal Stem Cells [MSC] Promote Nerve Regeneration

neurons

Researchers at Johns Hopkins University, Department of Plastic and Reconstructive Surgery find that mesenchymal stem cells [the type of stem cells found in teeth] promoted nerve regeneration in animal models [in this case – rodents] with paralyzing leg injuries.  According to the researchers, “Mesenchymal stem cells may be a promising add-on therapy to help damaged nerves regenerate.”  The study found that the rodents treated with their own stem cells responded best to the treatment. Those treated with donated cells from dissimilar rodent types – a situation most similar to human transplants – rejected their new limbs.

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