Multiple Sclerosis Treatment Becomes Canada’s First MS Stem Cell Clinical Trial.

The University of Ottawa trial infuses MSCs to reduce inflammation in the central nervous systems of MS patients.

The Multiple Sclerosis Society of Canada has funded Canada’s first stem cell clinical trial to treat multiple sclerosis, conducted by researchers at the University of Ottawa. The trial, called MESCAMS [Mesenchymal Stem Cell Therapy for Canadian MS patients], will comprise MSC infusions to the central nervous system to utilize their ability to regulate autoimmune attacks and reduce inflammation in 40 MS patients. Continue reading

Sniffing Out Parkinson’s Disease With Stem Cells

Stem Cells found in the nose produce neurons that may be able to treat neurodegenerative diseases.

German scientists at the University of Bielefeld and Dresden University of technology have produced neurons from inferior turbinate stem cells [ITSC], a cell type that is typically discarded during sinus surgery, as a potential treatment for Parkinson’s disease.  After transplanting the ITSCs into an animal model suffering from Parkinson’s, the researchers observed full functional restoration and significant behavioral recovery in the subjects without any adverse side effects. Continue reading

Multiple Sclerosis Trial Exhibits Positive Results of Stem Cell Therapy.

A five year phase II clinical trial has shown initial success in treating multiple sclerosis.

In a recent update of an ongoing five year clinical trial conducted by the Chicago Blood Cancer Institute, patients with relapsing-remitting multiple sclerosis have experienced suppression of disease-related inflammation as a result of hematopoietic stem cell transplantations.  The stem cells have the ability to regulate the autoimmune attack on the central nervous system, and have provided 82.8% of the patients with two years thus far of event-free disease remission. Continue reading

Singing the Praises of Stem Cell Research

Stem Cells in white crown sparrows used to study neurodegenerative diseases.

A research team from the University of Washington has discovered a stem cell signal in Gambel’s white-crown sparrows that may lead to new regenerative treatments for patient suffering from neurodegenerative diseases.  The team found that, in preparation for an upcoming mating season, the sparrow’s brain cells release a chemical signal that activates the division of neural stem cells, which facilitate peak singing performance to attract mates. Continue reading

Schizophrenia Studied With Human Stem Cells.

Scientists have differentiated stem cells into brain cells to study Schizophrenia.

Researchers from the University of California San Diego have differentiated stem cells into neurons to reach a new understanding of the mechanisms of schizophrenia.  The scientists harvested the stem cells of schizophrenia patients, differentiated them into brain cells, and then studied the cells on a dish to reveal that not only do stem cell-derived neurons emit neurotransmitters, but that several of these transmitters, such as dopamine, epinephrine, and norepinephrine, are secreted excessively in patients suffering from schizophrenia. Continue reading

Stem Cells Repair Damage via “First Aid Kits”

Scientists found that neural stem cells deliver restorative materials to other cells through vesicle transport.

In a recently published study, a team of researchers from the University of Cambridge has shown that neural stem cells are able to communicate and alleviate damage in other cells by transferring vesicles filled with molecules that enable the cells to repair themselves.  The cellular “first aid kits” contain proteins and nucleic acids that stimulate gene activation and signaling pathways to help the injured target cells survive. Continue reading

Multiple Sclerosis Therapy Incorporates Stem Cells in Clinical Trial

Mesenchymal Stem Cell Therapy has been deemed safe for patients suffering from multiple sclerosis.

A recent clinical trial conducted by the University of Genoa has determined that mesenchymal stem cell therapy to treat multiple sclerosis is indeed safe to perform on humans.  27 MS patients completed the study, which comprised an injection of the patient’s own [autologous] mesenchymal stem cells [MSCs] to reduce excessive inflammation caused by the patients’ own immune systems. None of the patients suffered any side effects from the injection. Continue reading

Multiple Sclerosis Therapy Incorporates Stem Cells in Clinical Trial

Mesenchymal Stem Cell Therapy has been deemed safe for patients suffering from multiple sclerosis.

A recent clinical trial conducted by the University of Genoa has determined that mesenchymal stem cell therapy to treat multiple sclerosis is indeed safe to perform on humans.  27 MS patients completed the study, which comprised an injection of the patient’s own [autologous] mesenchymal stem cells [MSCs] to reduce excessive inflammation caused by the patients’ own immune systems. None of the patients suffered any side effects from the injection. Continue reading

New York Times: The Eruption of Stem Cell Therapies.

Mr. Edgar Irastorza is one of thousands of people already benefiting from the progression of stem cell based therapies.

As reported on the front page of the New York Times Science section, clinical applications of stem cell based therapies are accelerating at a rate that will revolutionize the medical field in a matter of years.  In the United States alone, there are currently over 4000 therapies in clinical trials for the treatment of heart disease, blindness, spinal cord injuries, diabetes, H.I.V., and other diseases, injuries, and traumas. Continue reading

Ataxia Study Utilizes Autologous Stem Cells

A University of California PhD student has utilized stem cells to create a disease-on-a-chip model to study Ataxia.

Jackie Ward, a PhD student at the University of California, San Diego, has devised a method for studying rare neurological diseases, such as spinocerebeller ataxia. Ward developed a disease-on-a-dish model by harvesting stem cells from ataxic patients, differentiating them into the type of cell that is degenerated by ataxia, and then studying the progression of the disease. Continue reading