Scientists have devised a method of regenerating blood vessels by transplanting stem cells.
Researchers from the Indiana University School of Medicine have developed a potential therapy for peripheral artery disease by transplanting autologous [the patient’s own] stem cells. In an animal model, the transplanted stem cells differentiated into new blood vessels, which then restored blood flow to damaged tissues in the body. Continue reading →
Scientists have created light-sensitive retinal tissue from human stem cells.
A team of researchers from John Hopkins University of Medicine have developed miniature human retinal tissue in vitro with the ability to detect light. The scientists, led by Assistant Professor M. Valena Canto-Soler, constructed a 3D model of the retinal tissue containing photoreceptor stem cells that form light sensitive tissue in the back of the eye. Continue reading →
Scientists have treated heat-induced brain damage with stem cells.
A team of researchers at the Kaohsiung Medical University School of Dentistry have found that intravenous transplantation of dental pulp stem cells can protect against brain damage in heat stroke patients. Utilizing an animal model, scientists administered the treatment immediately post-heat stroke and observed several therapeutic effects, including a decrease in neurological damage, inflammation, and oxidative stress to the brain. Continue reading →
Researchers have found a way to use a patient’s own stem cells to ease the pain of osteoarthritis.
In a recent Phase 1 Clinical Trial, a team of researchers at the National University of Ireland, Galway, were successful in developing a treatment for osteoarthritis that utilizes autologous [the patient’s own] stem cells. According to Professor Frank Barry, scientific director of the Regenerative Medicine Institute at NUI Galway, “Using the patient’s own stem cells we have been able to treat their diseased joints and relieve their suffering and burden of pain.” Continue reading →
A new understanding of stem cell pathways can accelerate advances in reversing hearing loss.
Scientists from Harvard Medical School and the Massachusetts Eye and Ear Infirmary have found a signaling pathway that, when blocked, prevents the onset of noise-induced hearing loss and deafness. In an animal model, the inhibition of the pathway allowed stem cells in the inner ear to differentiate and regenerate sound-sensing hair cells, which are integral to the ability to hear. Continue reading →
Mesenchymal Stem Cell treatment has been shown to improve bone tissue formation in babies with osteogenesis imperfecta.
Researchers from Karolinska Institutet’s Department of Clinical Sciences have developed an application for mesenchymal stem cells [the same type found in Dental Stem Cells] to provide treatment for children born with osteogenesis imperfecta. The researchers utilized the unique properties of MSCs to facilitate and improve bone tissue formation through in utero transplantations. Continue reading →
The State of the Industry Briefing will review recent financial and clinical successes in stem cell research, as well as the field’s expectations in the new year.
The Alliance for Regenerative Medicine will be hosting the 4th Annual Regenerative Medicine Sate of the Union Briefing on January 13th in San Francisco. The public briefing will provide an in depth analysis of recent advances in stem cell therapy and the industry’s outlook for 2014. Continue reading →
Autologous stem cells eliminate the risk of bone loss and infection in hard to heal bone fractures
A study team from Kobe University Graduate School of Medicine in Japan has developed a treatment for hard to heal bone fractures. The treatment makes use of autologous [the patient’s own] stem cells to promote proper healing in fractures that fail to heal on their own. Continue reading →
Infusing stem cells into an organ structure allows it to be recognized by the patient’s immune system
Harvard Apparatus Regenerative Technology has developed a method to prevent rejection of organ donations without suppressing the patient’s immune system. By replacing the donor organ’s original cells with the patient’s own stem cells, the researchers can transplant the organ without an immune response. This avoids the need to place the patient in an immuno-compromised (vulnerable to disease) state. The method has successfully been utilized to replace cancerous tracheas and the company is expanding its methodology to other organs. Continue reading →
Mayo Clinic Researchers have used autologous stem cells to treat heart disease
Mayo Clinic researchers from the Center of Regenerative Medicine have utilized a patient’s own stem cells in a novel treatment for heart disease. The treatment involves harvesting the patient’s own stem cells, expanding and differentiating them in-vitro [outside the body] and transplanting them back into the patient. As a result of the successful initial study, a wider clinical trial is planned.