Pulmonary Valve for Children Engineered from Stem Cells.

An organic pulmonary valve replacement for children has been engineered with stem cells to grow as the child does to prevent multiple surgeries.

Researchers at the University Of Maryland School Of Medicine have created a pulmonary valve replacement for pediatric patients suffering from congenital heart conditions.  The scientists, led by Dr. David L. Simpson, differentiated the patient’s own [autologous] stem cells into heart valvular cells and then arranged these cells to bioengineer a pulmonary valve that was unique to each patient.  The valve was created in vitro [outside the body] so the next step would be to develop protocols to undertake clinical trials.  

Currently, inorganic pulmonary valve replacements cannot grow with the patient, often forcing children to undergo multiple replacement surgeries. Dr. Simpson’s use of autologous stem cells to create a patient-specific “living” replacement would allow the valve to grow as the patient does, eliminating the need for multiple open heart surgeries.  Additionally, the incorporation of autologous stem cells prevents the risk of an immune response after the valve is transplanted, further improving the outcome.

The University of Maryland’s research is yet another example of how autologous [a patient’s own] stem cells are influencing the outcome of treatment options. To learn more about stem cells, and how families can bank their own valuable stem cells by recovering the very powerful dental pulp stem cells during routine dental procedures; such as wisdom teeth extractions or the during the loss of baby teeth, visit StemSave or call 877-783-6728 (877-StemSave) today.



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