The University of Michigan, Michigan State, Wayne University, and Oakland University came together recently at the “Stem Cell Michigan Meeting” to discuss recent advances in the field of regenerative medicine.
“(Stem cells) change everything in medicine and have the chance to improve the quality of individual’s lives,” OU Professor and Beaumont Hospital ISCRM Coordinator Rasul Chaudhry said at the meeting.
Baxter International Inc. has initiated a phase III pivotal clinical trial to evaluate the use of adult autologous (an individual’s own) stem cells to increase exercise capacity in patients who suffer from chronic myocardial ischemia (CMI), a disease that results in reduced blood supply to the heart that can lead to long-term tissue damage and heart failure.
Dr. Jeremy Mao, StemSave’s Chief Science Advisor presented at the American Association for Dental Research (AADR) Annual Meeting in Tampa, FL this past week.
Dr Mao, DDS, PhD, a leading stem cell researcher and co-head of Columbia University’s Center for Craniofacial Regeneration, discussed several recent advances in stem cell dental treatments and the likely impact stem cells will have on the practice of dentistry.
Four-year-old Angela Irizarry was born with a single pumping chamber in her heart, a potentially lethal defect referred to medically as “hypoplastic left heart syndrome”. With just one pumping ventricle instead of the usual two, her body can’t deliver sufficient levels of oxygen to its organs and extremities, compromising her development and resulting in debilitating fatigue. Without surgical repair, says her pediatric surgeon Dr. Christopher Breuer, 70% of children with this defect die before their first birthday.
Unlike many other sources of stem cells, mesenchymal stem cells specifically have a large capacity for self-renewal while still maintaining their multipotency. They also give rise to an extensive variety of cell types, such as bone cells (osteocytes), cartilage cells (chondrocytes), fat cells (adipocytes), pancreatic islet cells and connective tissue cells such as those found in tendons.
A research article recently published by Dr. Arnold Caplan Ph.D, and Dr. Irina Kerkis Ph.D examines the proliferative capabilities and plasticity of stem cells found in both baby teeth (DTSC) and adult wisdom teeth( DPSC).
By examining the origin and development of both types of teeth, the researchers found that both baby and wisdom teeth are highly proliferative and plastic, making them conducive to cryo-preservation and future harvesting. The article notes that stem cells derived from baby teeth have particular proliferative capacity because of the high concentration of stem cells in young teeth.
Researchers at the University of Georgia have recently decoded the complex inner ‘wiring’ of stem cell differentiation. Despite the promise of therapeutic use of human stem cells shown in clinical trials, until now a complete understanding of the mechanisms that control the how and why stem cells differentiate in new cells was not fully known to scientists.
Dr. Dennis W. Lam, DDS, a StemSave provider, was recently featured in an article from New Jersey Family. He spoke on the importance and ease of investing in the future health of children by choosing to harvest the stem cells in their teeth.